
Vitamin B12 is central to red blood cell formation, neurological function, and energy production. When it dips, even into the low-normal range for a high-demand life, you see it: slower recovery, softer focus, and mood shifts that track with real numbers, not vague intuition.
At Physique26 in Beverly Hills, Vitamin B12 support is not a one-size-fits-all injection. It is a managed protocol that utilizes intramuscular injections for immediate correction and transdermal patches (SculptPatch) for steady, needle-free maintenance. Whether we are correcting a confirmed deficiency or supporting a patient in a high-output weight loss program, the goal is straightforward: align symptoms, labs, and delivery methods so patients know exactly why B12 is in their plan and what it is meant to do.
At Physique26, Vitamin B12 isn’t a branded “energy boost” slogan. It’s a physiological tool built for patients who expect performance and accountability.
Many patients come to Physique26 already on GLP-1 medications for medical weight loss, adjusting their nutrition, or balancing demanding careers with aggressive health goals. In that context, Vitamin B12 supports the body’s ability to keep up: it assists red blood cell production, oxygen delivery, and energy metabolism. For patients who travel frequently or prefer to avoid weekly needles, the inclusion of the SculptPatch allows for consistent dosing without a clinic visit, ensuring that "busy" doesn't mean "depleted."
Instead of treating Vitamin B12 as a standalone product, the team folds both injections and patches into a broader assessment that looks at symptoms, medical history, digestive function, and medications. It’s a small but critical piece of a structured approach that also considers protein, strength training, metabolic support, and realistic recovery windows.

Vitamin B12 is a water-soluble vitamin and an essential nutrient involved in DNA synthesis, red blood cell formation, and the protection of nerve cells. When levels are adequate, most people never think about it. When they’re low, or hovering at the low end of “normal” for a person with a demanding lifestyle, the cracks show up as fatigue, brain fog, reduced focus, mood shifts, and decreased exercise tolerance.
Because Vitamin B12 is tied so closely to the body’s metabolic processes and neurological function, Physique26 treats it as a measurable lever. The goal isn’t to chase extreme numbers; it’s to identify who may benefit based on real symptoms and context, then use the right delivery method (needle or patch) as an effective means of correction.
Diet plays a role. Patients who avoid animal foods, have a limited diet, or live with certain gut conditions are more at risk. So are those using medications that interfere with absorption. For patients already pushing hard in work and training, there’s less margin for quiet deficiencies.
For many patients, oral B12 is enough. For others, it isn’t. Absorption can be reduced by age, gut health, GI surgery, or medications, making direct delivery methods more reliable for restoring function.
At Physique26, we customize the route of administration to fit the patient’s lifestyle and biological needs:
The gold standard for fast correction and predictable serum levels. This method is ideal for patients with confirmed deficiency, those in active GLP-1 weight loss phases, or those needing immediate support. To sustain these levels and prevent energy dips, we typically recommend a monthly injection protocol.
A transdermal route that delivers Vitamin B12 through the skin in a controlled, time-released manner. Designed for daily application, the patch provides sustained efficacy for 8 hours, ensuring consistent delivery throughout the active part of your day. This is the preferred method for maintenance, frequent travelers, or patients who are needle-averse but still require higher bioavailability than oral pills can offer. (Available via our partner site, TheSkinSpot.com).
Your provider evaluates which route (or combination of routes) fits your physiology instead of defaulting to a single recommendation.
The process begins with a focused consultation (virtual or in person) to understand symptoms, medications, digestive factors, and any known risks for deficiency. Many Physique26 patients already have recent labs from their GLP-1 or metabolic programs, which makes it easier to see where B12 fits in the bigger picture.
If injections are appropriate, dosing isn’t guesswork. Deficiency usually calls for a defined weekly schedule followed by reassessment once fatigue, cognition, and neurological markers stabilize. Patients with normal labs but high-demand lifestyles may follow a more flexible “performance schedule” during busy work cycles, travel, or calorie-restricted phases.
Some patients transition to the SculptPatch once levels stabilize, using it as a maintenance tool that supports energy and metabolic output without sticking to a strict injection timeline. Others combine both: injections for correction, patches for between-visit support. The priority is clarity. Why each option is used, how long it’s needed, and what you should expect as levels normalize.

Used appropriately, Vitamin B12 can help improve energy in patients who are low or trending low-normal relative to their needs. Many patients report increased energy that feels steady rather than jittery, better focus and mental clarity in demanding work days, and improved mood when deficiency-driven fatigue and fog ease up.
For patients in active weight loss or GLP-1 programs, adequate B12 supports red blood cell formation, oxygen delivery, and energy production, which makes it easier to maintain movement, preserve lean mass, and engage with the plan instead of slipping into exhaustion. There can be secondary benefits to overall health and wellness markers when deficiency is corrected: better training quality, more stable mood, fewer days lost to drag.
What Vitamin B12 does not do here: it does not function as a stand-alone weight loss agent, and it is not sold as a cure-all for vague symptoms without proper evaluation. That line is non-negotiable.
For patients who prefer a needle-free option, the SculptPatch offers a transdermal route for steady Vitamin B12 delivery. It’s a maintenance-friendly choice for people who travel often, dislike injections, or want subtle support between in-office visits. It’s not a replacement for correcting deficiency, but it can help maintain energy, cognition, and metabolic output once levels are restored.

Vitamin B12 support at Physique26 is considered for patients with real indicators, not just anyone curious about a trend. You might be a good candidate if you:
In each case, the team looks at symptoms and your wider lifestyle before moving ahead. The aim is to determine when B12 will serve as meaningful metabolic support and when your energy issues point somewhere else entirely.
A Vitamin B12 Replenishment at Physique26 is quick and direct. The medication is administered intramuscularly in a controlled setting using a pharmacy-grade product. Mild soreness at the injection site is the most common effect. Serious reactions are rare and discussed openly, along with clear guidance on when to contact the team.
Because B12 is a water-soluble vitamin, excess is generally excreted in urine, but that doesn’t mean unlimited dosing is appropriate. Thoughtful protocols, real charts, and ongoing observation matter, especially when B12 is one piece of a more complex plan that may include GLP-1s, IV therapy partners, or other vitamin injections such as vitamin C-based blends for immune system or wellness support.
If you see B12 marketed as limitless, routine, and context-free, that’s a red flag. Here, it’s framed honestly: evidence-informed, monitored, and used with respect for the rest of your physiology.
There’s persistent confusion online about B12 as a fat-burning shot. In reality, Vitamin B12 supports weight loss indirectly for the right patient: by easing deficiency-driven fatigue, stabilizing neurological function, protecting red blood cell formation, and helping you maintain movement, structure, and adherence.
At Physique26, B12 is paired with GLP-1 protocols, nutrition coaching, and strength training guidance. It supports the body rather than pretending to replace real work. If your levels are already robust and your fatigue is tied to sleep or stress, you’ll hear that directly.

Frequency varies. Some patients need a focused course of weekly injections. Others transition to less frequent maintenance or shift to oral support once levels and symptoms normalize. Your provider will map this out so you understand the rationale and endpoint rather than feeling locked into indefinite visits.
Physique26 operates primarily as a self-pay model for Vitamin B12 injections and related services. Many patients use HSA or FSA funds. Major insurance providers and most PPO insurance plans typically do not cover B12 injections in this context, and the team won’t overstate coverage to win a booking. If you’d like documentation to submit to your PPO insurance plans, that can be discussed during your consultation. Transparency applies to billing as much as it does to dosing.

Choosing Vitamin B12 in Beverly Hills means you have options, from IV lounges to concierge practices. Physique26 stands as a physician-led program built inside a respected aesthetic and surgical environment, with protocols that already account for complex weight loss cases, metabolic health, and aesthetic outcomes.
Here, Vitamin B12 is:
The next step is simple: schedule a consultation with Physique26 to see if Vitamin B12 injections belong in your plan, or if your energy, mood, and focus call for a different strategy entirely.
Your provider reviews your symptoms, medical history, diet, and labs when indicated. If your levels and context don’t support injections, they’ll say so.
If deficiency or low-normal levels are contributing, correcting them can improve energy and clarity. If not, other causes are explored instead of overselling shots.
No. They may support metabolism and activity in the right patient, but they are not a stand-alone weight loss solution.
Many patients notice changes within days to a few weeks, depending on how deficient they were and how consistent the protocol is.
If IV vitamin support or IV drips are appropriate, your provider can discuss options and referrals. The priority is medical fit, not pushing add-ons.
Patients with specific allergies or rare conditions may not be candidates. Screening and consultation at Physique26 determine if B12 is appropriate for you.