
You understand your body better than anyone. You also know that constantly eating fewer calories can leave you tired and weak. Eventually, weight management is less about willpower and more about biology, and another cup of coffee won’t solve it. We offer a clinical approach that helps regulate blood sugar and manage your weight without draining your energy or reducing your muscle mass. In Beverly Hills, high performance matters. Our custom Semaglutide treatments help you reach your target weight without losing your vitality.
In clinical practice, a consistent pattern shows up. Patients lose weight—but not in the way they expected. Strength drops. Muscle softens. Metabolism slows.
What looks like success on the scale often reflects a mix of fat loss and lean mass loss.
That distinction matters.
Without hormonal regulation and a structured plan to preserve muscle, the body adapts aggressively. Energy expenditure declines. Hunger signals rise. And over time, weight regain becomes more likely.
A medical weight loss program built around GLP-1 physiology changes that equation entirely.

Semaglutide combined with Vitamin B12 or Glycine is a personalized medical weight loss plan. The GLP-1 medication supports appetite regulation and slows digestion, while the selected add-on may support energy or lean-mass goals during weight loss.
Cost | Downtime | Pain Level | Duration |
|---|---|---|---|
| Consultation required for exact pricing | None | Tiny mosquito bite | Once-weekly injection |
Fatigue and lean-mass loss can affect the weight-loss experience, which is why Physique26 personalizes treatment rather than using the same formulation for everyone. Depending on your needs, your provider may recommend Vitamin B12 or Glycine as part of a broader plan that also includes nutrition, strength support, and ongoing monitoring.

Vitamin B12 plays an important role in red blood cell production and normal energy metabolism. When appropriate, it can be included in the same injection to simplify a personalized treatment plan and support patients who may be vulnerable to low B12 or fatigue during weight loss.

Glycine is an amino acid involved in protein synthesis and other metabolic processes. When appropriate, it may be included as one part of a lean-mass support plan alongside adequate protein, resistance training, and careful dosing. Weight loss can still affect muscle and body volume, so we monitor progress and adjust the plan as needed.

We typically begin with the lowest appropriate dose and adjust gradually according to your response and tolerance. If progress plateaus, your provider may recommend a higher dose of Semaglutide under careful supervision.
You may have a high BMI or weight-related concerns such as high blood pressure. You already make thoughtful food choices but need medical help managing food cravings and appetite. You also want a plan that supports energy and lean-mass goals during weight loss.
Semaglutide is contraindicated for patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Your provider will also review your medical history, nutrition, activity level, and ability to follow the treatment plan before determining whether Semaglutide is appropriate for you.
Whether you come to our clinic or use our telemedicine service, you will get the same high standard of care.

The first effects start in your brain. In the first few days, you will feel less urge to snack. You may even find it easier to skip the bread basket at meals.
You might have mild nausea at first as your body adjusts to treatment. Your provider will personalize the formulation and dosing schedule with comfort and tolerability in mind.

The first few weeks focus on introducing treatment at a low dose. Some people notice changes in food cravings and appetite early, while visible weight loss may take longer. Results and timing vary, and your provider will adjust the plan according to your response.

Using the medication consistently can help support long-term weight management. Many patients remain on an individualized maintenance dose, with ongoing adjustments based on their response, goals, and clinical needs.
Yes, there are risks. GLP-1 medications slow digestion, which can upset your stomach if you eat big or processed meals. Fatigue can also happen, but we help manage it with B12. We reduce risks by increasing doses slowly and giving you ongoing support.
The cost depends on your dose and the specific treatment we make for you. Your fee includes your provider’s time, your custom plan, and your monthly medication. We don’t give flat rates online. You’ll get exact pricing at your first consultation, based on your needs.
Most diet plans focus on restricting your behavior and require a lot of willpower. Medical weight loss works differently by changing how your body functions. By controlling insulin and slowing digestion, the medication helps you prefer smaller, healthier meals instead of feeling deprived.

We believe in treating the whole person. Medication is paired with personalized formulation choices, nutrition guidance, strength support, and ongoing monitoring. Our goal is to help you pursue weight loss while also supporting daily energy, physical strength, and lean-mass preservation.
Vitamin B12 may reduce the chance of fatigue during a caloric deficit by supporting red blood cell production and normal energy metabolism. Your provider will determine whether it is an appropriate addition to your formulation.
Glycine is an amino acid involved in protein synthesis. When paired with adequate protein, resistance training, and appropriate dosing, it may help reduce lean-mass loss during weight loss, although changes in facial or body volume can still occur.
Yes. Your biological needs may shift during your treatment plan. We monitor your progress and can adjust your compounded formulation if you begin experiencing specific friction points like fatigue or muscle loss.
No. We offer nationwide telemedicine consultations. If our providers determine you are a safe candidate, we ship your monthly supply of compounded Semaglutide directly to your home.
Your provider may consider a higher dose if progress plateaus and you are tolerating the medication well. Most patients begin at the lowest appropriate dose, with any increases made gradually according to response and clinical judgment.